Daily Archives: October 13, 2014

Philips and Radboud university medical center debut wearable diagnostic prototype for chronic illness at Dreamforce 2014 event

— Co-developed prototype for proactive COPD patient management will run on Philips cloud-based HealthSuite Digital Platform

ANDOVER, Massachusetts, and SAN FRANCISCO, Oct. 13, 2014 /PRNewswire/ — Today at the Dreamforce 2014 conference in San Francisco, Royal Philips (NYSE: PHG; AEX: PHIA) and Nijmegen NL-based Radboud university medical center (Radboudumc) announced the debut of a prototype to support patients with chronic obstructive pulmonary disease (COPD). The launch marks the start of joint explorations between Philips and Radboudumc to apply mobile, digital and cloud technologies to improve patient outcomes, care coordination and patient empowerment across the health continuum.

Video – http://origin-qps.onstreammedia.com/origin/multivu_archive/PRNA/ENR/FX-MM35608-20141012-1.mp4
Video – http://origin-qps.onstreammedia.com/origin/multivu_archive/PRNA/ENR/FX-MM35608-20141012-2.mp4
Infographic – http://photos.prnewswire.com/prnh/20141012/151645-INFO
Logo – http://photos.prnewswire.com/prnh/20140122/NE50581LOGO

According to the US Centers for Disease Control and Prevention (CDC), 117 million Americans, or nearly one-half of the US adult population, have at least one chronic condition, and one in four adults has two or more.  The CDC estimates that caring for patients with chronic conditions accounts for 70% of the annual health care spend in the U.S.  In a study released by The World Economic Forum, the global economic impact of the five leading non-communicable diseases – cardiovascular disease, chronic respiratory disease, cancer, diabetes and mental ill-health – could total $47 trillion over the next 20 years.

Management of COPD is challenging and often costly, as the progressive nature of the disease leads many patients to require complicated therapies and frequent hospital readmissions. At the same time, consumers are increasingly looking for new ways to take control of their personal health in order to live healthier and better lives.

“Unlike other wearable solutions recently introduced to the market, this prototype collects more than just wellness data from otherwise healthy people,” said Jeroen Tas, CEO, Healthcare Informatics Solutions and Services, Philips. “We are demonstrating the power of harnessing both clinical and personal health information to better manage chronic disease patients across the health continuum, from healthy living, prevention, diagnosis, treatment, recovery and home care.”

How it works

The wearable diagnostic prototype for COPD patients feeds data collected from patients at home to clinicians through the Philips HealthSuite Digital Platform to two clinical applications currently available on the cloud-based platform – eCareCompanion and eCareCoordinator – which both recently received FDA 510(k) clearance. Once a COPD patient has left the hospital, a wearable diagnostic prototype collects data day and night – including physical activity/inactivity, respiratory indicator, heart rhythm and heart rate variability. That data is then sent via the cloud to the Philips HealthSuite Digital Platform, where it is shared with the appropriate care providers via the eCareCoordinator application, presenting a more complete view of the patient’s illness.

“Together with Philips, we are exploring and developing tools to enable patients to be true partners in their own health care, including Hereismydata™ and thus creating a digital platform for patients to collect data from EMRs as well as personal wearable technology,” said Lucien Engelen, director REshape Innovation Center at Radboud university medical center. “Our collaboration with Philips creates the scale needed for a globalizing sustainable healthcare approach.”

Radboudumc is considered to be one of the most innovative medical centers in Europe focused on digital solutions to enable patient centric care. The innovation center at Radboudumc, part of the network of Singularity University’s Exponential Medicine track in Silicon Valley, is at the forefront of the convergence of technology and patient empowerment, both inside and outside the hospital.  

As part of Philips vision for the HealthSuite Digital Platform, the company is working to create a suite of open application programming interfaces (APIs) that can be used by developers to create innovative applications for hospitals and health systems. Visitors to the Philips booth in the Salesforce Customer Showcase at Dreamforce can sign up to learn more about this Developers Toolkit, expected to be available in early 2015.

Members of the press and conference attendees can learn more about the Philips-Radboudumc  innovative COPD prototype at the Dreamforce 2014 conference in San Francisco from October 13-16: Demos will be shown at the Dreamforce Industry Health and Life Sciences Showcase (Moscone South/Gateway) and the Customer Showcase areas (Moscone West).

For updates on further platform developments, visit www.philips.com/dreamforce and follow the #DF14 conversation at @PhilipsHealth.

For further information, please contact:

Kathy O’Reilly
Philips
(o) 978-659-2638 (mobile) 978-221-8919
Kathy.oreilly@philips.com
Twitter: @kathyoreilly

Sabine van Deursen
Philips
+31 6 15043894
Sabine.van.deursen@philips.com
Twitter: @sabinevdeursen

Viola Peulen
Radboudumc
+31 24 3668799 (mobile) +31 6 55346484
Viola.peulen@radboudumc.nl

Salesforce and others are trademarks of salesforce.com, inc.

About Royal Philips:
Royal Philips (NYSE: PHG, AEX: PHIA) is a diversified health and well-being company, focused on improving people’s lives through meaningful innovation in the areas of Healthcare, Consumer Lifestyle and Lighting. Headquartered in the Netherlands, Philips posted 2013 sales of EUR 23.3 billion and employs approximately 112,000 employees with sales and services in more than 100 countries. The company is a leader in cardiac care, acute care and home healthcare, energy efficient lighting solutions and new lighting applications, as well as male shaving and grooming and oral healthcare. News from Philips is located at www.philips.com/newscenter.

About Radboud university medical center
Radboud university medical center is an institute for patient care, research and education & training, located in Nijmegen, the Netherlands. Our mission is to have a significant impact on healthcare. We aim to be a frontrunner in the development of innovative, sustainable and affordable healthcare. By offering excellent quality, participatory and personalized healthcare, operational excellence and sustainable networks. Our almost 10,000 employees and over 3,000 students do their utmost every day to make a positive contribution to the future of healthcare and medical sciences.

Related Links
Philips Presence at Dreamforce
Philips HealthSuite Digital Platform

Yew Bio-Pharm Signs Exclusive Distribution Agreement with Carpal Aid to Market Carpal Tunnel Syndrome Product in China

HARBIN, China, October 13, 2014 /PRNewswire/ — Yew Bio-Pharm Group, Inc. (“Yew Bio” or the “Company”) (OTCBB: YEWB), a major grower and seller of yew trees, yew raw materials used in the manufacture of traditional Chinese medicine (…

AmCham South China Kicks off its 2014 Charity Fundraising Effort with RMB400,000 from Mead Johnson and RMB 150,000 from Guangzhou CSG Glass

AmCham Effort to Save Lives of Orphaned Children in need of Immediate Life Saving Surgery, and Help Raise Changyuan Village in Guangdong Above the Poverty Line

GUANGZHOU, China, Oct. 13, 2014 /PRNewswire/ — The American Chamber of Commerce in South China (AmCham South China) today announced details of its annual charity fundraising effort. This year’s program is co-organized by the Guangzhou People’s Association for Friendship with Foreign Countries (under Guangzhou FAO), the Guangzhou Charity Association (under Guangzhou Civil Affairs Bureau) and the Guangzhou Women and Children’s Medical Center, aiming to raise donations of materiel and funds. The in-kind donations will be distributed in Guangdong’s impoverished Changyuan Village (part of Meizhou city) on the first quarter of 2015. Additionally, cash donations will be used to help poor villages and poor causes and finance medical treatments for orphaned children at the Guangzhou Women and Children’s Medical Center. All donations will go through Guangzhou Youth Development Foundation with proper receipts issued to the donors.

Charity Press Conference

Charity Press Conference

 

Charity Press Conference

Charity Press Conference

AmCham South China President Harley Seyedin disclosed the plans and beneficiaries. He also noted that weeks before the official launch, Mead Johnson Nutrition, had already pledged 400,000 yuan in cash. Guangzhou CSG Glass CO., Ltd also will contribute 150,000 yuan in cash to this charity effort.

Events planned under the cooperative effort include:

1. Press Conference, Oct 13th

– To inform the press and the public about the background and action plan of the Charity Theme Events and to build awareness of the need for philanthropy and to collect donations for initiating poverty alleviation projects in Changyuan Village and orphans in need of medical treatment.

– To call for more donors’ participation.

2. Inspection Tour of Changyuan Village, first quarter 2015

A corporate delegation with potential investors and experts will visit Changyuan Village for projects, accompanied by a team from the Guangzhou Women and Children’s Medical Center who will provide free medical services to villagers, and build awareness of the need for philanthropy.

About The American Chamber of Commerce in South China

The American Chamber of Commerce in South China (AmCham South China) is a non-partisan, non-profit organization dedicated to facilitating bilateral trade between the United States and the People’s Republic of China. Certified in 1995 by the U.S. Chamber of Commerce in Washington D.C., AmCham South China represents more than 2,300 corporate and individual members, is governed by a fully-independent Board of Governors elected from its membership, and provides dynamic, on-the-ground support for American and International companies doing business in South China. In 2013, AmCham South China hosted nearly 10,000 business executives and government leaders from around the world at its briefings, seminars, committee meetings and social gatherings. The American Chamber of Commerce in South China is a fully-independent organization accredited by the U.S. Chamber of Commerce in Washington, D.C. All AmChams in China are independently governed and represent member companies in their respective regions.

The mission of the American Chamber of Commerce in South China is to promote the development of trade, commerce and investment between the United States and the People’s Republic of China with a special focus on South China; to provide a forum in which member businesses can identify their common interests and discuss solutions for common problems; to work with and advocate member interests with relevant organizations in South China, elsewhere in China and the United States, and to set the standards for corporate social responsibility for the community that the Chamber serves.

About Mead Johnson Nutrition China Ltd

Mead Johnson Nutrition China was founded in 1993. Our manufacturing facility is located at Dong Ji Xia Yuan Road of Guangzhou Economic and Technological Development Zone. It covers an area of 60,000 square meters and boasts some of the world’s most advanced production processes and technology. Currently, the company’s sales network is established in 29 provinces, autonomous regions and municipalities nationwide.

Mead Johnson strives to advance its leadership role as part of the healthy growth of the entire pediatric nutrition industry. The company has operated strictly under its first-to-market “All-Rounded Safety” quality management model and GMP standards across its manufacturing, supply chains, storage and distribution networks. Having been awarded ISO9001:2000 certification, Mead Johnson China adheres to HACCP principles, meets national food safety and hygiene standards, and complies with all World Health Organization and U.S. Food and Drug Administration regulations for infant formula.

With deep roots in China extending back 21 years, Mead Johnson is committed to delivering professional care and support to Chinese consumers in need by providing high quality nutritional products for pregnant women, infants and children and sharing advanced knowledge through various customer activities to enhance the awareness of the importance of early childhood nutrition by young Chinese parents.

About Guangzhou Women and Children’s Medical Center

Guangzhou Women and Children’s Medical Center (GWCMC) was established with the integration of the former Guangzhou Children’s Hospital and former Guangzhou Maternity Health Care Center. Covering an area of 37 thousand square meters and a built-up area of 130 thousand square meters, the hospital is equipped with 1400 beds. Among the 2603 staff, 282 is holding senior titles, 573 has received master level education or above and 47 of them are MD or MS mentors. In December 2012, GWCMC became the first public hospital in southern China to earn JCI accreditation. 

Year 2013 witnessed 3.69 million outpatient visits, 73,200 discharges and 44,300 surgical operations. The hospital has evolved to be a high-level, comprehensive and multi-disciplinary health care institution, integrating the function of medical and healthcare, prevention, research and education.

“Caring for women and children with benevolence and expertise” remains at the core of the hospital’s mission. Our culture stems from the motto of “Integrity, Professionalism, Endeavor and Diligence”, and core value of “Love, harmony, prudence and practical”.

About the Guangzhou Charity Association-Guangzhou Civil Affairs Bureau

Founded in 1994, Guangzhou Charity Association is a registered citywide charitable society group approved by the municipal government. It is also a member of China Charity Federation.

The aim of the association is to promote the spirit of humanitarian, to contribute to poverty alleviation, to help people with less fortune and people in need, which indicates the progress and development of the society.

The mission of the organization is to host various charity events, to receive donations from at home and abroad, to assist the government to promote philanthropy, to establish different charity service institutions, and to host charity exchange events at home and abroad.

Since establishment, the award-winning organization contributed a lot to charity promotion, fund raising, emergency rescue, poverty alleviation, medical assistance as well as educational assistance which all yield great results. Till the end of 2013, the fund collected has reached 2.39 billion yuan, and the donated fund by the association has added up to 2.12 billion yuan.

About the Guangzhou People’s Association for Friendship with Foreign Countries (GZPAFFC)

The GZPAFFC is a division of the Guangzhou Foreign Affairs Office, which is overseen by the Ministry of Foreign Affairs. The Association’s primary duties include the implementation of national foreign affairs-related guidelines and policies, liaising with international non-governmental and economic organizations on behalf of the municipal government, the reception of visiting personnel and delegations from the same, the organization of outbound goodwill delegations, and “[the execution of] other tasks as instructed by the CPC Guangzhou Committee and Guangzhou Municipal Government“. More information about the Association can be found on the Guangzhou Foreign Affairs Office website (www.gzwaishi.gov.cn/Item/3993.aspx).

About Changyuan Village

Located in the west of Zhuanshui Town of Wuhua, a famous hometown of Chinese expatriates, Changyuan Village boasts 124.5 hectares of arable land, 68.9 hectares of which are paddy fields. Covering a mountain area of 134 hectares, Changyuan Village is home to 620 households, with the total population reaching up to 3,125. The villagers earn their livelihoods basically by growing rice locally and laboring as migrant workers outside the village. A preliminary household survey shows that 119 households of the village (627 people) currently live below the poverty line, accounting for 19.2% and 20.1% respectively of the total household number and the total village population. These 627 poverty-stricken villagers are thus designated as the focus of assistance in this new round of poverty-alleviating effort. The village is home to one primary school, namely, Changyuan Primary School, with 310 students and 16 teachers.

About Guangzhou Youth Development Foundation

Guangzhou Youth Development Foundation (Hereinafter referred to as GYDF) was founded in May 4th, 1994. This public foundation was co-founded by Guangzhou Committee of China’s Communist Youth League, Guangzhou Youth Federation and Guangzhou Working Committee of Young Pioneers. GYDF aims to rally fund and materials support for development of teenagers’ career by connecting with enterprise & public institutions, social organizations, other organizations and individuals home and abroad; to carry on helping orphans and the poor in their study; to develop First Aid service; to subsidize all districts and institutions to hold various activities which benefit for teenagers’ physical and psychological health; to support and promote studies of teenagers’ problems; to award excellent teenagers and social organizations and individuals who make contribution to teenagers’ career.   

Since its establishment, GYDF has taken an active participation in social welfare with support from different sectors of society. It promotes “Help the Disadvantaged”, devotes to building a harmonious society, dedicates in helping poor students to learn. When the whole nation was faced with natural disasters, GYDF united and led municipal youth to devote in earthquake relief. This manifests noble spirits of Guangzhou great love. Meanwhile, it has received guidance and assistance from central, provincial and municipal authorities.

Photo – http://photos.prnasia.com/prnh/20141013/0861407357-a
Photo – http://photos.prnasia.com/prnh/20141013/0861407357-b

1st and Largest Multi-country Study in Asia Reveals Patients Require Better Specialist Care and Pharmacotherapy to Treat the Growing Burden of Pain

– New Mundipharma Asia study highlights current shortfalls in diagnosis and treatment of pain

– ACHEON survey finds only 6% of patients suffering from Cancer Pain in Asia have been treated by pain specialists

– ACHEON study finds current physician pain assessment procedure and training remains inadequate in Asia

– 84% of physicians surveyed agreed that opioids should be the first line of therapy for cancer pain

SINGAPORE, Oct. 13, 2014 /PRNewswire/ — Results from the first and largest cross-sectional evaluation of physicians’ and patients’ perspectives on cancer and non-cancer pain management in 10 Asian countries have revealed the pressing need to improve pain diagnosis and management for patients in Asia.

Mundipharma, a multinational pharmaceutical leader in pain management, presented new data collected on physician and patient perception in its ACHEON study. Four posters, summarising data collected from 1158 physicians and 2495 patients across Asia in the Mundipharma-sponsored ACHEON[1] study, were presented at the International Association for the Study of Pain’s 15th World Congress on Pain in Buenos Aires, Argentina from 6-11 October 2014.

According to a 2009 World Health Organisation report, five billion people live in countries globally with low or no access to controlled medicines and have insufficient access to treatment for moderate to severe pain[2]. The ACHEON study has highlighted that barriers to optimising pain therapy are higher in Asian patients as compared to Western counterparts, raising concern over the shortfall in current treatment options and procedures[3].

The ACHEON survey found that improving physicians’ education and clinical knowledge in pain assessment and opioid use would improve the consistency and accuracy of the pharmacotherapy used to treat the majority of chronic-pain sufferers whose quality of life is significantly affected by their condition.

463 of the physicians recruited in the ACHEON survey were involved in the management of cancer pain and 30% of these considered their medical school training on cancer pain management and opioid use to be inadequate, highlighting the need for better medical school training and continuing medical education (CME) opportunities on pain-related topics in Asia.

  • 84% of those physicians agreed that opioids should be the first line of therapy for cancer pain

1190 patients with Cancer Pain were assessed using measurements of activities of daily living, sleeping patterns, concentration and focus, overall quality of life (QoL), performance at work and employment status.

  • 70% claimed that their performance at work was impacted by pain
  • 42% had stopped work due to their cancer pain
  • 84% of patients had never been referred to a pain clinic
  • Less than half of the patients had had their pain assessed according to a scale and only 6% had been treated by pain specialists

These findings confirm the impact of pain as a significant socioeconomic burden in Asian patients and show the imperative need to improve current clinical practices via adequate pain assessment and optimisation of treatment.

Chronic non-cancer pain (CNCP) is a highly prevalent condition with incidence rates as high as 40 – 50% in older adults[4][5] and the treatment of chronic pain is further complicated by the under-diagnosis and the complexity of patient modalities even in the most advanced nations.  CNCP is a substantial cause of morbidity, globally.

695 physicians involved in the management of CNCP were evaluated in the ACHEON survey to establish their attitudes towards pain management and prescribing habits, particularly opioid prescriptions.

  • 71% of these reported that they had received less than ten hours of CME related to pain management in the last year
  • 32% considered their medical school training on opioid use to be inadequate

Opioid therapy has shown benefits in short-term trials in patients with osteoarthritis and neuropathic pain; however, clinical skills and adequate knowledge are warranted to maximise opioid effectiveness due to safety concerns[6][7][8].

  • 64% of the physicians surveyed said that opioids were necessary for the treatment of CNCP

Furthermore, under-diagnosed and under-treated CNCP is highly prevalent in clinical practice. Analysis of a group of 1305 CNCP patients evaluated their current pain levels, type of pain, attitudes towards pain and levels of satisfaction with their treatment. Most patients included in the survey had moderate to severe CNCP for a median duration of 2 years that had a significant detrimental impact on the quality of life.

  • 65% of patients reported that no pain scale was used by their physicians to assess their pain, relying only on a subjective assessment
  • Despite the high intensity of pain reported, only 4% of patients receiving pharmacotherapy reported being prescribed opioids.

Hanlim Moon, Head of Medical Affairs Mundipharma, Asia Pacific, Latin America, Middle East and Africa, commented: “The results from the ACHEON study clearly demonstrate the need for improved pain management practices in Asia. By accessing feedback from patients and physicians in this first anonymous, unbiased survey we have been to identify the shortcomings in the way pain is currently treated.  Based on the findings, we are able to adapt the way that we at Mundipharma can support our broad portfolio of pain medications with training and education, strengthening our patient-centric approach to pain management.”

Raman Singh, President, Asia Pacific, Latin America, Middle East, and Africa, commented: “Pain, acute and chronic, is a hugely debilitating illness which affects a significant proportion of the population in Asia and the ACHEON survey results confirm our findings in relation to the large and growing need to improve the current practices of pain management.

“At Mundipharma we consider it our responsibility to ensure that physicians and patients get the best possible opportunity to treat pain with the best training, practices and medications.  We are already proactively investing in the education of all stakeholders through a diverse information program, including our regional Pain Forums, Pain Focus website, an educational online portal for both healthcare professionals and patients, as well as our Pain Assessment via Pain Scale initiatives, and look forward to building upon our initiatives throughout Asia.”

For further information please contact:

Stephenie Vasko
Communications Director – Asia, Latin America & Middle East
PH +65-6303-9732
stephenie.vasko@mundipharma.com.sg

www.mundipharma.com.sg

About ACHEON

The non-interventional, anonymous, non-biased ACHEON survey was the first and largest cross-sectional evaluation of physicians’ and patients’ perspectives on cancer and non-cancer pain management in 10 Asian countries (China, Hong Kong, Indonesia, Korea, Malaysia, Philippines, Singapore, Taiwan, Thailand and Vietnam).

About Mundipharma

The Mundipharma network of independent associated companies consists of privately owned companies and joint ventures covering the world’s pharmaceutical markets. These companies are committed to bringing to patients the benefits of pioneering treatment options in the core therapy areas of oncology, pain, respiratory and rheumatoid arthritis.  http://www.mundipharma.com.sg/

About Cancer Pain

Pain in cancer may arise from a tumor compressing or infiltrating tissue; from treatments and diagnostic procedures; or from skin, nerve and other changes caused by a hormone imbalance or immune response. At any given time, about half of all patients with malignant cancer are experiencing pain, and two thirds of those with advanced cancer experience pain of such intensity that it adversely affects their sleep, mood, social relations and activities of daily living.[9][10][11]

About IASP

IASP is the leading professional forum for science, practice, and education in the field of pain, bringing together scientists, clinicians, health-care providers, and policymakers to stimulate and support the study of pain and to translate that knowledge into improved pain relief worldwide.

About the World Congress on Pain

The World Congress on Pain is the premier congress devoted to the research and treatment of pain with the purpose of: providing a state-of-the-art overview of a wide range of topics in the area of pain; offering practical reviews of current research and therapies; providing continuing education credits for clinicians; and allowing delegates to participate in formal and informal discussions with international experts on pain management and pain research.

Posters presented
 
Copies of the posters will be made available on request to Lois.Ward@mundipharma-rd.eu

PF470/PF470 Current Practices for Cancer Pain Management in Asia: a Physician’s Perspective
Y. C. Kim et al. (2014)
Friday, October 10, 2014 9:30 – 10:30 AM

PF341/PF341 Current Practices of Chronic Non-cancer Pain Management: Physicians’ Perspectives from a Pan Asian Survey
C. W. Cheung et al. (2014)
Friday, October 10, 2014 3:15 – 4:15 PM

PF404/PF404 Patients’ Perspectives on the Current Status of Cancer Pain Management in Asia
L. M. Tho et al. (2014)
Friday, October 10, 2014 9:30 – 10:30 AM

PS109/PS109 Patients’ Perspectives on Chronic Non-cancer Pain Management in Asia
E. O. Salido et al. (2014)
Saturday, October 11, 2014 3:15 – 4:15 PM

[1] CURRENT PRACTICES OF CANCER AND CHRONIC NON-CANCER PAIN MANAGEMENT: A PAN-ASIAN STUDY (ACHEON STUDY)

[2] World Health Organization Briefing Note — February 2009. Access to Controlled Medications Programme

[3] Chen CH, Tang ST, Chen CH. Meta-analysis of cultural differences in Western and Asian patient-perceived barriers to managing cancer pain. Palliat Med 2012;26(3):206–21.

[4] International Association for the Study of Pain. Unrelieved pain is a major global healthcare problem. http://www.efic.org/userfiles/Pain%20Global%20Healthcare%20Problem.pdf

[5] Helme RD, Gibson SJ. The epidemiology of pain in elderly people. Clin Geriatr Med 2001;17:417–31.

[6] Furlan AD, Sandoval JA, Mailis-Gagnon A, Tunks E. Opioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects. CMAJ 2006;174(11):1589–94.

[7] Avouac J, Gossec L, Dougados M. Efficacy and safety of opioids for osteoarthritis: A meta-analysis of randomized controlled trials. Osteoarthritis Cartilage 2007;15:957–965

[8] Eisenberg E, McNichol ED, Carr DM. Efficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin. JAMA 2005;293:3043–3052.

[9]  Hanna, Magdi; Zylicz, Zbigniew (Ben), eds. (1 January 2013). Cancer Pain. Springer. pp. vii & 17. ISBN 978-0-85729-230-8.

[10] Marcus DA. Epidemiology of cancer pain. Curr Pain Headache Rep. 2011;15(4):231-4. doi:10.1007/s11916-011-0208-0. PMID 21556709.

[11] Sheinfeld Gorin S, Krebs P, Badr H, et al. (February 2012). “Meta-analysis of psychosocial interventions to reduce pain in patients with cancer”. J. Clin. Oncol. 30 (5): 539–47. doi:10.1200/JCO.2011.37.0437. PMID 22253460.